Article

Regulation of Cathelicidin Antimicrobial Peptide (CAMP) Gene Expression by TLR9 in Adipocytes and in Adipose Tissue

2023-05-22

Abstract excerpt

Understanding the complex interactions between metabolism and the immune system (“meta-flammation”) is crucial for the identification of key immunomodulatory factors as potential therapeutic targets in obesity and in cardiovascular diseases. Cathelicidin antimicrobial peptide (CAMP) is an important factor of innate immunity and is expressed in adipocytes. CAMP therefore might play a role as an adipokine in metafla...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3df47834-4cd8-5a77-81a5-60ef743a5c8d
DOI: 10.20944/preprints202305.1459.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Regulation of Cathelicidin Antimicrobial Peptide (CAMP) Gene Expression by TLR9 in Adipocytes and in Adipose TissueDOI 10.20944/preprints202305.1459.v1Read

MicroRNA-10a-5p regulates macrophage polarization and promotes therapeutic adipose tissue remodelingSemantic proximity Read

Eicosapentaenoic Acid Regulates Inflammatory Pathways through Modulation of Transcripts and miRNA in Adipose Tissue of Obese MiceSemantic proximity Read

The cAMP Pathway as Therapeutic Target in Autoimmune and Inflammatory DiseasesSemantic proximity Read

Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis.Semantic proximity Read

Increased energy expenditure and protection from diet-induced obesity in mice lacking the cGMP-specific phosphodiesterase, PDE9Semantic proximity Read

Chemerin – exploring a versatile adipokineSemantic proximity Read

PPARγ activation by lipolysis-generated ligands is required for cAMP dependent <i>UCP1</i> induction in human thermogenic adipocytesSemantic proximity Read

Involvement of multiple signaling pathways in the post-bariatric induction of IL-6 and IL-8 mRNA and release in human visceral adipose tissueSemantic proximity Read

A role for TLR10 in obesity and adipose tissue morphology.Semantic proximity Read

Visceral fat adipocytes from obese and colorectal cancer subjects exhibit distinct secretory and ω6 polyunsaturated fatty acid profiles and deliver immunosuppressive signals to innate immunity cells.Semantic proximity Read

Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4.Semantic proximity Read

Anti-inflammatory effects of α-MSH through p-CREB expression in sarcoidosis like granuloma modelSemantic proximity Read