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MicroRNA-10a-5p regulates macrophage polarization and promotes therapeutic adipose tissue remodeling

27 Aug 2019

Abstract excerpt

OBJECTIVE: This study investigated the role of microRNAs generated from adipose tissue macrophages (ATMs) during adipose tissue remodeling induced by pharmacological and nutritional stimuli. METHODS: Macrophage-specific Dicer knockout (KO) mice were used to determine the roles of microRNA generated in macrophages in adipose tissue remodeling induced by the β3-adrenergic receptor agonist CL316,243 (CL). RNA-seq...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 31668395
DOI: 10.1016/j.molmet.2019.08.015

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