Plasma neurofilament analysis in VITALITY-ALS

Abstract excerpt

Objective: To evaluate correlations between neurofilament (Nf) concentrations and clinical characteristics and disease progression using a large longitudinal dataset from VITALITY-ALS (ClinicalTrials.gov identifier: NCT02496767), a 48-week, randomized, double-blind, placebo-controlled clinical trial of tirasemtiv in people with ALS (pALS). Methods: Plasma was collected at baseline and every 8 weeks thereafter....

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