Article

Genetic analysis of lung cancer reveals novel susceptibility loci and germline impact on somatic mutation burden

2021-04-30

Abstract excerpt

<h4>ABSTRACT</h4> Germline genetic variants are involved in lung cancer (LC) susceptibility. Previous genome-wide association studies (GWAS) have implicated genes involved in smoking propensity and DNA repair but further work is required to identify additional LC susceptibility variants and to investigate LC disease development dynamics. We have undertaken a family history-based genome-wide association (GWAx) stud...

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Literature Corpus work: 3dd6ac85-98d0-5453-98d2-f50641918cd5
DOI: 10.1101/2021.04.26.21254132

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