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Article

Lung cancer and DNA repair genes: multilevel association analysis from the International Lung Cancer Consortium.

Carcinogenesis - 1 May 2012

Kazma Rémi, Babron Marie-Claude, Gaborieau Valérie, Génin Emmanuelle, Brennan Paul, Hung Rayjean J, McLaughlin John R, Krokan Hans E, Elvestad Maiken B, Skorpen Frank, Anderssen Endre, Vooder Tõnu, Välk Kristjan, Metspalu Andres, Field John K, Lathrop Mark, Sarasin Alain, Benhamou Simone

Abstract excerpt

Lung cancer (LC) is the leading cause of cancer-related death worldwide and tobacco smoking is the major associated risk factor. DNA repair is an important process, maintaining genome integrity and polymorphisms in DNA repair genes may contribute to susceptibility to LC. To explore the role of DNA repair genes in LC, we conducted a multilevel association study with 1655 single nucleotide polymorphisms (SNPs) in...

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Source

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Identifiers

PMID: 22382497
DOI: 10.1093/carcin/bgs116
PMCID: PMC3334518

Genes

MSH5
POLB
POLN
RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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