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Article

Rate of Pathogenic Germline Variants in Patients With Lung Cancer.

JCO precision oncology - 1 Sept 2023

Sorscher Steven, LoPiccolo Jaclyn, Heald Brandie, Chen Elaine, Bristow Sara L, Michalski Scott T, Nielsen Sarah M, Lacoste Alix, Keyder Emil, Lee Hayan, Nussbaum Robert L, Martins Renato, Esplin Edward D

Abstract excerpt

PURPOSE: Germline genetic testing (GGT) is now recommended for all patients diagnosed with ovarian or pancreatic cancer and for a large proportion of patients based solely on a diagnosis of colorectal or breast cancer. However, GGT is not yet recommended for all patients diagnosed with lung cancer (LC), primarily because of a lack of evidence that supports a significant frequency of identifying pathogenic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37992258
DOI: 10.1200/PO.23.00190
PMCID: PMC10681406

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