Article

Evaluating Genomic Polygenic Risk Scores for Childhood Acute Lymphoblastic Leukemia in Latinos

2023-06-12

Abstract excerpt

<h4>ABSTRACT</h4> The utility of polygenic risk score (PRS) models has not been comprehensively evaluated for childhood acute lymphoblastic leukemia (ALL), the most common type of cancer in children. Previous PRS models for ALL were based on significant loci observed in genome-wide association studies (GWAS), even though genomic PRS models have been shown to improve prediction performance for a number of complex d...

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Literature Corpus work: 3dd45487-a078-53ca-a029-f47cb927c672
DOI: 10.1101/2023.06.08.23291167

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