Article

Strong Components of Epigenetic Memory in Cultured Human Fibroblasts Related to Site of Origin and Donor Age

2015-08-25

Abstract excerpt

Differentiating pluripotent cells from fibroblast progenitors is a potentially transformative tool in personalized medicine. We previously identified relatively greater success culturing dura-derived fibroblasts than scalp-derived fibroblasts from postmortem tissue. We hypothesized that these differences in culture success were related to epigenetic differences between the cultured fibroblasts by sampling location...

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Literature Corpus work: 3d567495-d8ac-57ee-a6cc-6c27fd9bd50b
DOI: 10.1101/025288

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