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iPSC Preparation and Epigenetic Memory: Does the Tissue Origin Matter?

11 Jun 2021

Abstract excerpt

The production of induced pluripotent stem cells (iPSCs) represent a breakthrough in regenerative medicine, providing new opportunities for understanding basic molecular mechanisms of human development and molecular aspects of degenerative diseases. In contrast to human embryonic stem cells (ESCs), iPSCs do not raise any ethical concerns regarding the onset of human personhood. Still, they present some technical...

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PMID: 34208270
DOI: 10.3390/cells10061470

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