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Article

Strong Components of Epigenetic Memory in Cultured Human Fibroblasts Related to Site of Origin and Donor Age.

PLoS genetics - 1 Feb 2016

Ivanov Nikolay A, Tao Ran, Chenoweth Joshua G, Brandtjen Anna, Mighdoll Michelle I, Genova John D, McKay Ronald D, Jia Yankai, Weinberger Daniel R, Kleinman Joel E, Hyde Thomas M, Jaffe Andrew E

Abstract excerpt

Differentiating pluripotent cells from fibroblast progenitors is a potentially transformative tool in personalized medicine. We previously identified relatively greater success culturing dura-derived fibroblasts than scalp-derived fibroblasts from postmortem tissue. We hypothesized that these differences in culture success were related to epigenetic differences between the cultured fibroblasts by sampling...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26913521
DOI: 10.1371/journal.pgen.1005819
PMCID: PMC4767228

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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