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Insights into the mysterious genetic variation profile of <i>tprK</i> in <i>Treponema pallidum</i> under the development of natural human syphilis infection

2019-01-31

Abstract excerpt

Although the variations of the tprK gene in Treponema pallidum were considered to play a critical role in the pathogenesis of syphilis, how actual variable characteristics of tprK in the course of natural human infection enabling the pathogen’s survive has thus far remained unclear. Here, we performed NGS to investigate tprK of T. pallidum directly from primary and secondary syphilis samples. Compared with di...

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Literature Corpus work
3d38faf1-396f-5ffe-ac25-6101c4eaad1d
DOI
10.1101/536573
Open publication

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