Article

Profile of the <i>tprK</i> gene in primary syphilis patients based on next-generation sequencing

2018-09-19

Abstract excerpt

<h4>Background</h4> The highly variable tprK gene of Treponema pallidum has been acknowledged to be the cause of persistent infection. Previous studies mainly focused on the heterogeneity in tprK in propagated strains using a clone-based Sanger approach. Few studies have investigated tprK directly from clinical samples using deep sequencing. <h4>Methods/Principal findings</h4> We conducted a comprehensive a...

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Literature Corpus work: 5e55c9b4-ca1e-5498-9fc7-d18324806d19
DOI: 10.1101/422162

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