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<i>Treponema pallidum</i> subsp. <i>pallidum</i> genetic population structure and relevance to syphilis prevention and treatment

2026-04-28

Abstract excerpt

Syphilis, caused by the spirochete Treponema pallidum subsp. pallidum (TPA), is resurging globally, particularly in low- and middle-income countries. However, TPA genomic diversity and population structure in these settings remain poorly characterized. We investigated the global genetic diversity of syphilis spirochetes, sequencing 298 new TPA genomes from 11 countries across five continents, including underrep...

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Literature Corpus work
46b24eb2-3723-58a9-b844-0fbc14d7725d
DOI
10.64898/2026.04.27.26351061
Open publication

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