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Article

Tracing the origin of Treponema pallidum in China using next-generation sequencing.

Oncotarget - 12 Jul 2016

Sun Jun, Meng Zhefeng, Wu Kaiqi, Liu Biao, Zhang Sufang, Liu Yudan, Wang Yuezhu, Zheng Huajun, Huang Jian, Zhou Pingyu

Abstract excerpt

Syphilis is a systemic sexually transmitted disease caused by Treponema pallidum ssp. pallidum (TPA). The origin and genetic background of Chinese TPA strains remain unclear. We identified a total of 329 single-nucleotide variants (SNVs) in eight Chinese TPA strains using next-generation sequencing. All of the TPA strains were clustered into three lineages, and Chinese TPA strains were grouped in Lineage 2 based...

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Identifiers

PMID: 27344187
DOI: 10.18632/oncotarget.10154
PMCID: PMC5189996

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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