Article

<i>TREM2</i> is thyroid hormone regulated making the TREM2 pathway druggable with ligands for thyroid hormone receptor

2021-01-27

Abstract excerpt

Triggering receptor expressed on myeloid cells-2 (TREM2) is a cell surface receptor on macrophages and microglia that senses and responds to disease associated signals to regulate the phenotype of these innate immune cells. The TREM2 signaling pathway has been implicated in a variety of diseases ranging from neurodegeneration in the central nervous system to metabolic disease in the periphery. We report here that...

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Literature Corpus work: 3d0ea743-ef53-567b-bbb3-b206cd5f53ee
DOI: 10.1101/2021.01.25.428149

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<i>TREM2</i> is thyroid hormone regulated making the TREM2 pathway druggable with ligands for thyroid hormone receptorDOI 10.1101/2021.01.25.428149Read

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