Article

Paeonol enhances macrophage phagocytic function by modulating lipid metabolism through the P53-TREM2 axis

2023-05-12

Abstract excerpt

<h4>Background: </h4> The emerging concept of immunometabolism highlights the interplay between lipid metabolism and phagocytosis in macrophages. Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) has been identified as an important modulator of both lipid metabolism and phagocytic function in macrophages. This study aims to investigate the roles of P53 and TREM2 in regulating macrophage lipid metabolism and...

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Literature Corpus work: ed988870-afa2-5190-be40-8d706624e02a
DOI: 10.21203/rs.3.rs-2872809/v1

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