Article

Polycystin-2 (TRPP2) Regulates Primary Cilium Length in LLC-PK1 Renal Epithelial Cells

2020-02-25

Abstract excerpt

Polycystin-2 (PC2, TRPP2) is a Ca 2+ permeable non-selective cation channel whose dysfunction generates autosomal dominant polycystic kidney disease (ADPKD). PC2 is present in different cell locations, including the primary cilium of renal epithelial cells. Little is known, however, as to whether PC2 contributes to the structure of the primary cilium. Here, we explored the effect(s) of external Ca 2+ , PC2 chann...

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Literature Corpus work: 3cfa3745-45e0-5a9b-b6ea-f3784423b1a2
DOI: 10.1101/2020.02.24.962860

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