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Article

Polycystin-2 cation channel function is under the control of microtubular structures in primary cilia of renal epithelial cells.

The Journal of biological chemistry - 8 Dec 2006

Li Qiang, Montalbetti Nicolás, Wu Yuliang, Ramos Arnolt, Raychowdhury Malay K, Chen Xing-Zhen, Cantiello Horacio F

Abstract excerpt

Mutations in the gene encoding polycystin-2 (PC2) result in autosomal dominant polycystic kidney disease and defects in left-right asymmetry during embryogenesis. PC2 is a TRP-type Ca(2+)-permeable non-selective cation channel, which is expressed in kidney and other organs. PC2 is present and fun...

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Identifiers

PMID: 16950792
DOI: 10.1074/jbc.M603643200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16950792-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Polycystin-2 cation channel function is under the control of microtubular structures in primary cilia of renal epithelial cells.PMID 16950792Read ↗

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