Article

Colonoscopy Yields in ATM Pathogenic Variant Carriers: Insights from a Hereditary Cancer Registry Cohort

2026-06-05

Abstract excerpt

<title>Abstract</title> <p>Ataxia-telangiectasia mutated (ATM) is a moderate-penetrance DNA damage repair gene associated with increased risk of several malignancies, particularly breast and pancreatic cancer. Its relationship with colorectal neoplasia remains uncertain, and current guidelines recommend average-risk colorectal cancer screening for heterozygous ATM carriers. Real-world colonoscopic outcomes in thi...

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Literature Corpus work: 3cec117e-dd92-5ae5-aa14-3ff371cc5636
DOI: 10.21203/rs.3.rs-9837975/v1

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