Article

G-Quadruplex and i-Motif Structures in the <i>SHMT1</i> 5’UTR Modulate Gene Expression

2025-11-26

Abstract excerpt

Multiple sclerosis (MS) is a fatal neurodegenerative disease that progresses by eroding the myelin sheath and exposing the neuron, leading to neuronal degradation and death. While MS remains without an effective treatment or cure, studies have identified genes that are dysregulated in MS patients and predicted to be involved with disease progression. These genes are primarily involved in controlling DNA methylatio...

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Literature Corpus work: 3ce97a95-29a9-5e04-ad50-2f2d800e5cde
DOI: 10.1101/2025.11.24.690261

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