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Article

MGMT-Methylation in Non-Neoplastic Diseases of the Central Nervous System

8 Apr 2021

Abstract excerpt

-methylguanine-DNA methyltransferase (MGMT) promoter methylation plays an essential role in assessing the potential efficacy of alkylating agents in the chemotherapy of malignant gliomas. MGMT promoter methylation is considered to be a characteristic of subgroups of certain malignancies but has also been described in various peripheral inflammatory diseases. However, MGMT promoter methylation levels have not yet...

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PMID: 33917711
DOI: 10.3390/ijms22083845

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