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The rs4759314 SNP within Hotair lncRNA is associated with risk of multiple sclerosis.

Multiple sclerosis and related disorders - 1 May 2020

Taheri Mohammad, Noroozi Rezvan, Sadeghpour Saba, Omrani Mir Davood, Ghafouri-Fard Soudeh

Abstract excerpt

Recent studies have demonstrated the role of long non-coding RNAs (lncRNAs) in the pathophysiology of autoimmune disorders such as multiple sclerosis (MS). Among these transcripts is HOX transcript antisense intergenic RNA (HOTAIR) whose contribution in MS has been verified both in animal models and in human studies. In the current study, we genotyped three single nucleotide polymorphisms (SNPs) with this lncRNA...

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PMID: 32058948
DOI: 10.1016/j.msard.2020.101986

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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