Article

Altered visual function in a larval zebrafish knockout of neurodevelopmental risk gene <i>pdzk1</i>

2020-09-22

Abstract excerpt

The human PDZK1 gene is located in a genomic susceptibility region for neurodevelopmental disorders. A genome-wide association study (GWAS) identified links between PDZK1 polymorphisms and altered visual contrast sensitivity, an endophenotype for schizophrenia and autism spectrum disorder. The PDZK1 protein is implicated in neurological functioning, interacting with synaptic molecules including post-synaptic den...

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Literature Corpus work: 3ce20bba-fa45-53de-96e0-a7ab273c611a
DOI: 10.1101/2020.09.21.307405

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