Article

Atrial Fibrillation Polygenic Risk Score (AF-PRS) Predicts Non-Ischemic Cardiomyopathy: A Single-Center Retrospective Cohort Study of 16,801 Individuals

2026-03-24

Abstract excerpt

<h4>Background</h4> Non-ischemic cardiomyopathy (NICM) represents a major cause of heart failure with limited tools for early risk stratification. Atrial fibrillation (AF) is a well-established contributor to cardiomyopathy but is often clinically silent in its early stages. The atrial fibrillation polygenic risk score (AF-PRS) reflects genetic susceptibility to AF and may identify individuals at risk for AF-rela...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3c9b9312-0139-535a-8bb0-0629f8684946
DOI: 10.64898/2026.03.20.26348938

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Atrial Fibrillation Polygenic Risk Score (AF-PRS) Predicts Non-Ischemic Cardiomyopathy: A Single-Center Retrospective Cohort Study of 16,801 IndividualsDOI 10.64898/2026.03.20.26348938Read

Cardiomyopathy Gene Variants and Polygenic Risk Scores in Atrial Fibrillation: Evidence for an Atrial-First Phenotype.Semantic proximity Read

Cardiomyopathy-Associated Gene Variants in Atrial Fibrillation.Semantic proximity Read

Clinical and Genetic Risk Factors Predict Atrial Fibrillation on the Basis of Hypertrophic Cardiomyopathy.Semantic proximity Read

Polygenic risk-based prediction of heart failure in young patients with atrial fibrillation: an analysis from UK BiobankSemantic proximity Read

Combining polygenic and clinical risk scores in atrial fibrillation risk prediction: Implications for population screening.Semantic proximity Read

Monogenic and Polygenic Contributions to Cardiomyopathy and Heart Failure Across Diverse PopulationsSemantic proximity Read

Novel Genes Associated With Atrial Fibrillation and the Predictive Models for AF Incorporating Polygenic Risk Score and PheWAS-Derived Risk Factors.Semantic proximity Read

Heritability of Atrial Fibrillation.Semantic proximity Read

Polygenic risk scores in atrial fibrillation: Associations and clinical utility in disease prediction.Semantic proximity Read

Unbiased characterization of atrial fibrillation phenotypic architecture provides insight to genetic liability and clinically relevant outcomesSemantic proximity Read

Identification of Novel Genes Associated with Atrial Fibrillation and Development of Atrial Fibrillation Predictive Models by Incorporating Polygenic Risk Scores and PheWAS-Derived Risk FactorsSemantic proximity Read

Genomic approaches to identify and investigate genes associated with atrial fibrillation and heart failure susceptibility.Semantic proximity Read