Article
Polygenic risk-based prediction of heart failure in young patients with atrial fibrillation: an analysis from UK Biobank
15 May 2025
Abstract excerpt
AIMS: Heart failure (HF) is the most concerning morbidity in atrial fibrillation (AF) through mutual influence on a poor prognosis. A polygenic risk score (PRS) has recently been proposed to improve the risk prediction for cardiovascular disease. The additive predictive role of PRS for incident HF in patients with AF who inherently carry a high risk of HF is unknown. METHODS AND RESULTS: From the UK Biobank, we...
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