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GLP-1 analogs restore inflammatory, mitochondrial and intercellular signaling networks in the <i> Snca <sup>G51D/G51D</sup> </i> knock-in mouse model of Parkinson’s disease

2026-05-19

Abstract excerpt

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by a prolonged prodromal stage that culminates in motor deficits. Current PD therapies primarily alleviate symptoms, underscoring the need for disease-modifying strategies. Glucagon-like peptide-1 (GLP-1) analogs showed early promise as candidate disease modifiers, but recent clinical results have been inconsistent, and their mechanism of actio...

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Literature Corpus work
3bc8df5c-0b5f-5355-bba2-dc1f5287a1e4
DOI
10.64898/2026.05.18.726024
Open publication

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GLP-1 analogs restore inflammatory, mitochondrial and intercellular signaling networks in the <i> Snca <sup>G51D/G51D</sup> </i> knock-in mouse model of Parkinson’s diseaseDOI 10.64898/2026.05.18.726024
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