Article

A new synuclein-transgenic mouse model for early Parkinson’s reveals molecular features of preclinical disease

2020-04-05

Abstract excerpt

Understanding Parkinson’s disease (PD) in particular in its earliest phases is important for diagnosis and treatment. However, human brain samples are collected post-mortem, reflecting mainly end stage disease. Because brain samples of mouse models can be collected at any stage of the disease process, they are useful to investigate PD progression. Here, we compare ventral midbrain transcriptomics profiles from α...

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Literature Corpus work: 67eea4fc-e15e-59b0-b502-9669b12df955
DOI: 10.1101/2020.04.04.016642

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