Article

Widespread Historical Contingency in Influenza Viruses

2016-08-19

Abstract excerpt

In systems biology and genomics, epistasis characterizes the impact that a substitution at a particular location in a genome can have on a substitution at another location. This phenomenon is often implicated in the evolution of drug resistance or to explain why particular ‘disease-causing’ mutations do not have the same outcome in all individuals. Hence, uncovering these mutations and their locations in a genome...

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Literature Corpus work: 3b4c4e9f-bbdf-5d9b-8245-fde963b92ff7
DOI: 10.1101/070094

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