Article

Altered Cardiac Neural Crest Migration Patterning in a Left Atrial Ligation Model of Hypoplastic Left Heart Syndrome

2026-03-14

Abstract excerpt

Cardiac neural crest cells (CNCCs) contribute to key cardiac structures during embryonic development. Disruption of CNCC patterning or function can lead to congenital heart defects. Here, we investigate whether hemodynamic perturbation alters CNCC behavior in chick embryos. We use the left atrial ligation model to modify intracardiac blood flow in the early common-atrium, common-ventricle heart and track retrovira...

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Literature Corpus work: 3b2ca75f-2fae-5e42-85af-124316319de9
DOI: 10.64898/2026.03.11.711140

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