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Article

<i>Fgf8</i>is required for pharyngeal arch and cardiovascular development in the mouse

1 Oct 2002

Abstract excerpt

We present here an analysis of cardiovascular and pharyngeal arch development in mouse embryos hypomorphic for Fgf8. Previously, we have described the generation of Fgf8 compound heterozygous (Fgf8(neo/-)) embryos. Although early analysis demonstrated that some of these embryos have abnormal left-right (LR) axis specification and cardiac looping reversals, the number and type of cardiac defects present at term...

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PMID: 12223417
DOI: 10.1242/dev.129.19.4613

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