Article
Neural crest and cardiovascular development: a 20-year perspective.
Birth defects research. Part C, Embryo today : reviews - 1 Feb 2003
Hutson Mary Redmond, Kirby Margaret L
Abstract excerpt
BACKGROUND: Twenty years ago this year was the first publication describing a region of neural crest cells necessary for normal cardiovascular development. Ablation of this region in chick resulted in persistent truncus arteriosus, mispatterning of the great vessels, outflow malalignments, and hypoplasia or aplasia of the pharyngeal glands. METHODS: We begin with a historical perspective and then review the...
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