Article

Multiple Causal Variants Underlie Genetic Associations in Humans

2021-05-25

Abstract excerpt

<h4>ABSTRACT</h4> The majority of associations between genetic variation and human traits and diseases are non-coding and in strong linkage disequilibrium (LD) with surrounding genetic variation. In these cases, a single causal variant is often assumed to underlie the association, however no systematic assessment of the number of causal variants has been performed. In this study, we applied a massively parallel r...

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Literature Corpus work: 3b0a25b6-336b-5d63-815a-b1863d4c2428
DOI: 10.1101/2021.05.24.445471

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