Article

Haplotype rather than single causal variants effects contribute to regulatory gene expression associations in human myeloid cells

2025-01-30

Abstract excerpt

<h4>ABSTRACT</h4> Genome-wide association studies typically identify hundreds to thousands of loci, many of which harbor multiple independent peaks, each parsimoniously assumed to be due to the activity of a single causal variant. Fine-mapping of such variants has become a priority and since most associations are located within regulatory regions, it is also assumed that they colocalize with regulatory variants t...

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Literature Corpus work: 16b5f47c-fd26-5b03-8b12-d53101b73f18
DOI: 10.1101/2025.01.30.635675

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