Article

Genetic colocalization atlas points to common regulatory sites and genes for hematopoietic traits and hematopoietic contributions to disease phenotypes

2019-09-30

Abstract excerpt

<h4>Background</h4> Genetic associations link hematopoietic traits and disease end-points, but most causal variants and genes underlying these relationships are unknown. Here, we used genetic colocalization to nominate loci and genes related to shared genetic signal for hematopoietic, cardiovascular, autoimmune, neuropsychiatric and cancer phenotypes. <h4>Results</h4> Our findings recapitulate developmental hema...

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Literature Corpus work: b1e4457a-b55e-5160-97fb-cade2d352946
DOI: 10.1101/787333

Open publication

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