Article

Let’s Tweap again: Economic and SNP retrieval optimisation for target enrichment of ancient DNA

2026-01-16

Abstract excerpt

Advancements in ancient DNA (aDNA) research have enabled the recovery of individual human genomes through target enrichment approaches. Despite the decreasing cost of next-generation sequencing, enrichment methods targeting single-nucleotide polymorphisms (SNPs) compiled in RNA/DNA hybrid panels remain costly and require further authentic optimisations. Here, we present the Tweap ( Tw ist ch eap ) protocol as a...

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Literature Corpus work: 3aec3881-5592-5b17-966b-a05291d88aa1
DOI: 10.64898/2026.01.15.699081

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