Article

In-solution Y-chromosome capture-enrichment on ancient DNA libraries

2017-11-22

Abstract excerpt

<h4>Background</h4> As most ancient biological samples have low levels of endogenous DNA, it is advantageous to enrich for specific genomic regions prior to sequencing. One approach – in-solution capture-enrichment – retrieves sequences of interest and reduces the fraction of microbial DNA. In this work, we implement a capture-enrichment approach targeting informative regions of the Y chromosome in six human arch...

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Literature Corpus work: c2a84927-940b-5c66-a661-5a30b920f93b
DOI: 10.1101/223214

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