Article

Three Reagents for in-Solution Enrichment of Ancient Human DNA at More than a Million SNPs

2022-01-15

Abstract excerpt

In-solution enrichment for hundreds of thousands of single nucleotide polymorphisms (SNPs) has been the source of >70% of all genome-scale ancient human DNA data published to date. This approach has made it possible to generate data for one to two orders of magnitude lower cost than random shotgun sequencing, making it economical to study ancient samples with low proportions of human DNA, and increasing the rate o...

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Literature Corpus work: 2debf16b-6f86-5024-b375-748fb686d7a2
DOI: 10.1101/2022.01.13.476259

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