Article
Improving access to endogenous DNA in ancient bone and teeth
2015-02-06
Abstract excerpt
Poor DNA preservation is the most limiting factor in ancient genomic research. In the vast majority of ancient bones and teeth, endogenous DNA molecules only represent a minor fraction of the whole DNA extract, rendering traditional shot-gun sequencing approaches cost-ineffective for whole-genome characterization. Based on ancient human bone samples from temperate and tropical environments, we show that an initial...
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Identifiers and source
- Literature Corpus work
- faa4b953-ffce-5f26-9a04-a1b0ee5386c7
- DOI
- 10.1101/014985