Article

Optimised in-solution enrichment of over a million ancient human SNPs

2024-05-16

Abstract excerpt

In-solution hybridisation enrichment of genetic markers is a method of choice in paleogenomic studies, where the DNA of interest is generally heavily fragmented and contaminated with environmental DNA, and where the retrieval of genetic data comparable between individuals is challenging. Here, we benchmarked the commercial “Twist Ancient DNA” reagent from Twist Biosciences using sequencing libraries from ancestral...

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Literature Corpus work: 04be3ff2-956d-5d8d-8cc0-cf1fded46ec9
DOI: 10.1101/2024.05.16.594432

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