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Article

Allelic bias when performing in-solution enrichment of ancient human DNA.

Molecular ecology resources - 1 Nov 2023

Davidson Roberta, Williams Matthew P, Roca-Rada Xavier, Kassadjikova Kalina, Tobler Raymond, Fehren-Schmitz Lars, Llamas Bastien

Abstract excerpt

In-solution hybridisation enrichment of genetic variation is a valuable methodology in human paleogenomics. It allows enrichment of endogenous DNA by targeting genetic markers that are comparable between sequencing libraries. Many studies have used the 1240k reagent-which enriches 1,237,207 genome-wide SNPs-since 2015, though access was restricted. In 2021, Twist Biosciences and Daicel Arbor Biosciences...

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PMID: 37712846
DOI: 10.1111/1755-0998.13869

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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