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Article

A SNP panel for coanalysis of capture and shotgun ancient DNA data.

Genome research - 1 Sept 2026

Fournier Romain, Pearson Fulton Alice, Tabin Daniel, Reich David

Abstract excerpt

Advances in technology have decreased the cost of generating genetic data from ancient people, resulting in exponentially increasing numbers of individuals with whole-genome data. However, these technologies come with platform-specific biases, limiting coanalyzability of individuals sequenced with different technologies as well as joint analysis of modern and ancient individuals. Here, we present a method to...

Read the complete abstract on PubMed

Topics

Polymorphism, Single Nucleotide
Humans
DNA, Ancient
Genome, Human
Shotgun Sequencing
Sequence Analysis, DNA
High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42586760
DOI: 10.1101/gr.281262.125

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