Article

Physiological cerebrospinal fluid like medium reveals autophagy dependency of leukaemia in the central nervous system

2026-03-11

Abstract excerpt

Nutrient availability is a critical environmental factor that influences the metabolism and adaptability of cancer cells, including acute lymphoblastic leukaemia (ALL) cells, prone to relapse in the central nervous system (CNS). Currently available cell culture media contain supraphysiological nutrient levels and do not represent the restricted metabolic environment of CNS-ALL which resides in the leptomeninges su...

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Literature Corpus work: 3acd0b68-9dd6-56d5-bb46-32d3394dced7
DOI: 10.64898/2026.03.09.709824

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