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Article

Sex differences in physiological response to increased neuronal excitability in a knockin mouse model of pediatric epilepsy.

Clinical science (London, England : 1979) - 21 Feb 2024

Hammer Michael F, Krzyzaniak Collin T, Bahramnejad Erfan, Smelser Kiran J, Hack Joshua B, Watkins Joseph C, Ronaldson Patrick T

Abstract excerpt

BACKGROUND: Epilepsy is a common neurological disease; however, few if any of the currently marketed antiseizure medications prevent or cure epilepsy. Discovery of pathological processes in the early stages of epileptogenesis has been challenging given the common use of preclinical models that induce seizures in physiologically normal animals. Moreover, despite known sex dimorphism in neurological diseases,...

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Identifiers

PMID: 38348743
DOI: 10.1042/CS20231572
PMCID: PMC10881277

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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