Article

Multivariate genotypic analyses that identify specific genotypes to characterize disease and control groups in ADNI

2017-12-18

Abstract excerpt

<h4>INTRODUCTION</h4> Genetic contributions to Alzheimer’s Disease (AD) are likely polygenic and not necessarily explained by uniformly applied linear and additive effects. In order to better understand the genetics of AD, we require statistical techniques to address both polygenic and possible non-additive effects. <h4>METHODS</h4> We used partial least squares-correspondence analysis (PLS-CA)—a method designed...

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Literature Corpus work: 3a7a26c4-cbde-57da-926f-3d92acd7f91c
DOI: 10.1101/235945

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