Decoding the Genetic Comorbidity Network of Alzheimer's Disease

Abstract excerpt

<title>Abstract</title> <p>Alzheimer's disease (AD) has emerged as the most prevalent and complex neurodegenerative disorder among the elderly population. However, the genetic comorbidity etiology for AD remains poorly understood. In this study, we conducted pleiotropic analysis for 41 AD phenotypic comorbidities, identifying ten genetic comorbidities with 16 pleiotropy genes associated with AD. Through biologica...

Topics

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• Aging
• Alzheimer Disease
• Chronic Disease
• Cohort Studies
• Genetic Predisposition to Disease
• Genetics, Aging, and Longevity in Model Organisms
• Genome-Wide Association Study
• Risk Factors

Identifiers and source

Literature Corpus work

01d60a3e-ea7c-56ad-9403-e37d1f62e481

DOI

10.21203/rs.3.rs-4820203/v1