Article
Gut-derived Lipopolysaccharide Promotes Alcoholic Hepatosteatosis and Subsequent Hepatocellular Carcinoma by Stimulating Neutrophil Extracellular Traps Through TLR4
2021-12-09
Abstract excerpt
<title>Abstract</title> <p>BackgroundBinge drinking leads to many disorders, including alcoholic hepatosteatosis, which is characterized by intrahepatic neutrophil infiltration and which increases the risk of hepatocellular carcinoma (HCC). Molecular mechanisms may involve the migration of bacterial metabolites from the gut to the liver and activation of neutrophil extracellular traps (NETs). MethodsSerum from bo...
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Identifiers and source
- Literature Corpus work
- 3a56fd58-dbac-5e39-a80f-15dc979dda79
- DOI
- 10.21203/rs.3.rs-1124551/v1
