Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neutrophil extracellular traps in hepatocellular carcinoma are enriched in oxidized mitochondrial DNA which is highly pro-inflammatory and pro-metastatic

1 Jan 2022

Abstract excerpt

Background: Neutrophil extracellular traps (NETs) are net like extracellular structure formed by neutrophils in response to certain stimulation. It works as inflammatory regulator and metastasis promoter in cancer. Mitochondrial-(mt)DNA is a circular, mitochondria derived double strain molecule, which is involved in NETs formation. Its role in NETs induced inflammatory alteration in hepatocellular carcinoma (HCC)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune cells in cancer
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Share to Nitric Oxide and Endothelin Effects

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35281873
DOI: 10.7150/jca.64170

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neutrophil extracellular traps in hepatocellular carcinoma are enriched in oxidized mitochondrial DNA which is highly pro-inflammatory and pro-metastaticPMID 35281873Read ↗

Neutrophil Extracellular Traps Promote a Liver Metastatic Phenotype in Human Colorectal Cancer Cells through Epithelial – Mesenchymal TransitionSemantic proximity Read ↗

CD61 + LDNs drive cancer metastasis by upregulating CCDC25 expression via DNA-TLR9-NF-kB axis in HCCSemantic proximity Read ↗

The emerging role of neutrophil extracellular traps in cancer: from lab to wardSemantic proximity Read ↗

NETosis as an oncologic therapeutic target: a mini reviewSemantic proximity Read ↗

Neutrophils in Cancer and Potential Therapeutic Strategies using Neutrophil-derived ExosomesSemantic proximity Read ↗

DNA of Neutrophil Extracellular Traps Binds TMCO6 to Impair CD8+ T-cell Immunity in Hepatocellular CarcinomaSemantic proximity Read ↗

Neutrophil Extracellular Traps in Cancer Therapy ResistanceSemantic proximity Read ↗

Clinical implications and pathological associations of circulating mitochondrial DNA.Semantic proximity Read ↗

Neutrophil Extracellular Traps Promote T Cell Exhaustion in the Tumor Microenvironment.Semantic proximity Read ↗

Neutrophil extracellular traps in cancerSemantic proximity Read ↗

OPA1 drives ROS-dependent neutrophil extracellular trap formation to promote tumor immunotherapy resistanceSemantic proximity Read ↗

Targeting neutrophils: Mechanism and advances in cancer therapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.