Article
Significant positive association of endotoxemia with histological severity in 237 patients with non-alcoholic fatty liver disease.
Alimentary pharmacology & therapeutics - 1 Jul 2017
Pang J, Xu W, Zhang X, Wong G L-H, Chan A W-H, Chan H-Y, Tse C-H, Shu S S-T, Choi P C-L, Chan H L-Y, Yu J, Wong V W-S
Abstract excerpt
BACKGROUND: Patients with nonalcoholic steatohepatitis (NASH) have gut dysbiosis and intestinal bacterial overgrowth. AIM: To test the hypothesis that endotoxemia is associated with the histological severity of nonalcoholic fatty liver disease (NAFLD) and determine factors associated with endotoxemia. METHODS: The endotoxemia markers lipopolysaccharide-binding protein (LBP) and endotoxin levels were measured in...
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