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Article

Establishment of animal models for NASH and utilization for mining associated gut microbiota

2022-07-26

Abstract excerpt

<title>Abstract</title> <p>A high-fat diet (HFD) animal model has an indispensable role in the research of gut-liver axis by generating an imbalance of gut microbiota and intestinal leakage, resulting in translocation of harmful bacterial metabolites and lipopolysaccharides (LPSs) to the liver, triggering immune responses, and stimulating non-alcoholic steatohepatitis (NASH). Replacing trans-fat with palm oil in...

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Literature Corpus work
74b28925-945b-56fa-abcc-7e8bed648ac4
DOI
10.21203/rs.3.rs-1826044/v1
Open publication

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