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A microbial metabolite reduces alcohol-induced inflammation via dual modulation of NF-κB and Interferon pathway

2026-06-23

Abstract excerpt

<h4>Background and aims</h4> Alcohol-associated hepatitis (AH) is characterized by excessive inflammation and blunted antiviral interferon (IFN) responses. We hypothesized that specific gut microbiome-derived metabolites could selectively enhance interferon signaling while limiting NF-κB mediated inflammation, thereby restoring immune balance in AH. Our goal is to identify microbiome-derived metabolites that diff...

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Literature Corpus work
ac25a029-3253-5121-80c8-4b5367945b1a
DOI
10.64898/2026.06.18.733199
Open publication

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A microbial metabolite reduces alcohol-induced inflammation via dual modulation of NF-κB and Interferon pathwayDOI 10.64898/2026.06.18.733199
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